Providing guests with cars for rent, Rex Hotel Boutique Tirana is approximately a 10-minute walk from the 1789–1823 Et'hem Bey Mosque. The hotel, located in the immediate vicinity of House of Leaves Historical Museum, is also at a proximity to Xhamia Dine Hoxha.

This hotel is about 20 km from Tirana International Mother Teresa airport and 550 metres from such cultural venues as the large National Museum of History. The Orthodox Cathedral of the Resurrection of Christ is a few steps from the Rex Hotel Boutique Tirana, while Kombinat Lines bus stop is merely 5 minutes' walk away. The property is 1.2 km from the Pyramid of Tirana.

The rooms comprise a sitting area complete with an air conditioner, as well as a flat-screen TV with satellite channels and pay-per-view channels. Furnished with a wardrobe and a writing table, they also have a stone fireplace and sound-proof windows. Bathroom amenities include a roll-in shower, a separate toilet, and a sink, along with comforts such as a hair dryer and bath sheets. Guests can enjoy views of the city from Rex Hotel Boutique.

Continental breakfast is offered each morning. Corner Shoshi offers Italian dishes and is situated 200 metres away.